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PfSPZ Challenge

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Malaria Trial in Bamako (Chloroquine Phosphate, PfSPZ Challenge, Pyrimethamine)

Completed
  • Malaria
  • Chloroquine Phosphate
  • +4 more
  • Bamako, Mali
    Malaria Vaccine Center STTB/MRTC
Jun 21, 2022

Healthy Trial in Leiden (M5717, PfSPZ Challenge, Placebo)

Completed
  • Healthy
  • Leiden, Netherlands
    Leiden University Medical Center
Feb 8, 2022

Malaria, Malaria,Falciparum Trial in Baltimore (PfSPZ Vaccine, PfSPZ Challenge (7G8), Normal Saline)

Recruiting
  • Malaria
  • Malaria,Falciparum
  • PfSPZ Vaccine
  • +2 more
  • Baltimore, Maryland
    University of Maryland, Baltimore, Center for Vaccine Developmen
Nov 2, 2022

Malaria Trial (Pyronaridine Tetraphosphate, Artesunate Drug Combination, PfSPZ Challenge (NF54), MVA ME-TRAP)

Not yet recruiting
  • Malaria
  • Pyronaridine Tetraphosphate, Artesunate Drug Combination
  • +4 more
  • (no location specified)
Jun 27, 2022

Malaria Trial in Seattle (PfSPZ Vaccine, PfSPZ Challenge (7G8) for CHMI, Normal Saline)

Completed
  • Malaria
  • PfSPZ Vaccine
  • +2 more
  • Seattle, Washington
    Fred Hutchinson Cancer Research Center
Jul 15, 2022

Malaria,Falciparum Trial in Kilifi (R21/Matrix-M, ChAd63/MVA ME-TRAP, intradermal injection (ID) or direct venous injection

Recruiting
  • Malaria,Falciparum
  • R21/Matrix-M
  • +2 more
  • Kilifi, Kenya
    KEMRI/Wellcome Trust Programme, Centre for Geographic Medicine R
Sep 14, 2022

Malaria Trial run by the NIAID (Chloroquine Phosphate, Pyrimethamine, Sanaria PfSPZ Challenge)

Completed
  • Malaria
  • Chloroquine Phosphate
  • +2 more
  • Bethesda, Maryland
    National Institutes of Health Clinical Center
May 5, 2021

Malaria,Falciparum Trial in Kilifi (PfSPZ Challenge, Sulfadoxine-Pyrimethamine, Piperaquine)

Not yet recruiting
  • Malaria,Falciparum
  • PfSPZ Challenge
  • +4 more
  • Kilifi, Kenya
    KEMRI-Wellcome Trust Research Programme
May 17, 2022

Malaria Trial in Antwerpen (P218 (1000 mg) Oral Capsules, Placebo Oral Capsules, P218 (100 mg) Oral Capsules)

Completed
  • Malaria
  • P218 (1000 mg) Oral Capsules
  • +3 more
  • Antwerpen, Belgium
    SGS Belgium NV Clinical Pharmacology Unit
Mar 16, 2021

Malaria Trial in Bamako (biological, drug, other)

Completed
  • Malaria
  • PfSPZ Vaccine
  • +5 more
  • Bamako, Mali
    University of Bamako (USTTB/MRTC)
Apr 19, 2021

Plasmodium Falciparum, Malaria Trial in Tübingen (DSM265 400mg, Placebo to DSM265 400 mg, Plasmodium falciparum sporozoite

Completed
  • Plasmodium Falciparum, Malaria
  • DSM265 400mg
  • +3 more
  • Tübingen, Germany
    Universitätsklinikum Tübingen, Institut für Tropenmedizin
Jan 7, 2021

Malaria,Falciparum, Parasitemia, Protozoan Infections Trial in Antwerpen (Artemether-Lumefantrine 20 Mg-120 Mg Oral Tablet,

Completed
  • Malaria,Falciparum
  • +3 more
  • Artemether-Lumefantrine 20 Mg-120 Mg Oral Tablet
  • PfSPZ-DVI Challenge
  • Antwerpen, Belgium
    SGS Belgium NV Clinical Pharmacology Unit
Sep 3, 2021

Healthy Trial in Seattle (DSM265, Placebo, Sporozoites)

Completed
  • Healthy
  • Seattle, Washington
    Fred Hutchinson Cancer Research Center - Prevention Center
Jan 13, 2022

Plasmodium Falciparum Infection Trial in Seattle (drug, biological, other)

Completed
  • Plasmodium Falciparum Infection
  • Seattle, Washington
    Kaiser Permanente Washington Health Research Institute - Vaccine
Dec 24, 2019

Plasmodium Falciparum Trial (atovaquone-proguanil)

Withdrawn
  • Plasmodium Falciparum
  • (no location specified)
May 6, 2020

Plasmodium Falciparum Infection Trial in Sikasso (drug, biological, other)

Completed
  • Plasmodium Falciparum Infection
  • Sikasso, Mali
    University of Bamako - Epidemiology of Parasitic Diseases - Mala
Nov 27, 2019

Malaria Trial in Santiago De Baney (PfSPZ Vaccine, Normal saline, PfSPZ Challenge (for CHMI))

Completed
  • Malaria
  • PfSPZ Vaccine
  • +2 more
  • Santiago De Baney, Bioko Island, Equatorial Guinea
    Baney Clinical Research Center
Jan 3, 2020

Malaria Trial (drug, biological, other)

Completed
  • Malaria
  • atovaquone/proguanil 250mg/100mg (A/P)
  • +2 more
  • (no location specified)
Jul 11, 2019

Malaria Trial in Fajara (PfSPZ Challenge)

Completed
  • Malaria
  • PfSPZ Challenge
  • Fajara, Gambia
    MRC Unit
Jan 15, 2019

Malaria Trial in Tübingen (PfSPZ Vaccine, PfSPZ Challenge (NF54), PfSPZ Challenge (7G8))

Completed
  • Malaria
  • PfSPZ Vaccine
  • +3 more
  • Tübingen, Germany
    Institute of Tropical Medicine, University of Tuebingen, Wilhelm
Jan 31, 2019

Malaria, Malaria,Falciparum Trial in Bagamoyo (PfSPZ Vaccine, Normal Saline Placebo, PfSPZ Challenge)

Completed
  • Malaria
  • Malaria,Falciparum
  • PfSPZ Vaccine
  • +2 more
  • Bagamoyo, Tanzania
    Bagamoyo Research and Training Center of the Ifakara Health Inst
Apr 3, 2019

Plasmodium Falciparum Infection Trial in Baltimore (PfSPZ (7G8) Challenge, PfSPZ (NF54) Challenge)

Completed
  • Plasmodium Falciparum Infection
  • PfSPZ (7G8) Challenge
  • PfSPZ (NF54) Challenge
  • Baltimore, Maryland
    University of Maryland School of Medicine - Center for Vaccine D
Jan 24, 2019

Malaria Trial in Malabo (PfSPZ Vaccine, PfSPZ Challenge (for CHMI), Normal Saline)

Completed
  • Malaria
  • PfSPZ Vaccine
  • +3 more
  • Malabo, Equatorial Guinea
    La Paz Medical Center
Oct 10, 2018

Malaria Trial in Bagamoyo (PfSPZ Vaccine, Normal Saline, PfSPZ Challenge (for CHMI))

Completed
  • Malaria
  • PfSPZ Vaccine
  • +2 more
  • Bagamoyo, Tanzania
    Bagamoyo Research and Training center of the Ifakara Health Inst
Oct 10, 2018

Malaria Trial in Baltimore (VRC-MALMAB0100-00-AB, CHMI)

Completed
  • Malaria
  • Baltimore, Maryland
    University of Maryland Baltimore, Center for Vaccine Development
Nov 9, 2022